{"id":897,"date":"2018-12-23T21:14:35","date_gmt":"2018-12-23T13:14:35","guid":{"rendered":"https:\/\/www.liu.world\/?page_id=897"},"modified":"2024-12-16T17:12:31","modified_gmt":"2024-12-16T22:12:31","slug":"%e6%b5%8b%e5%ba%8f","status":"publish","type":"page","link":"https:\/\/www.liu.world\/?page_id=897","title":{"rendered":"\u6d4b\u5e8f"},"content":{"rendered":"<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-909 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu01.jpg\" alt=\"\" width=\"689\" height=\"461\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu01.jpg 689w, https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu01-300x201.jpg 300w\" sizes=\"auto, (max-width: 689px) 100vw, 689px\" \/><\/p>\n<p style=\"text-align: left;\">\u57fa\u56e0\u6d4b\u5e8f\u6307\u5206\u6790\u7279\u5b9aDNA\u7247\u6bb5\u7684\u78b1\u57fa\u5e8f\u5217\uff0c\u5373\u817a\u560c\u5464\u3001\u80f8\u817a\u5627\u5576\u3001\u80de\u5627\u5576\u4e0e\u9e1f\u560c\u5464\u7684\u6392\u5217\u65b9\u5f0f\u3002<\/p>\n<p style=\"text-align: center;\"><strong>\u57fa\u56e0\u5bb6\u8c31<\/strong><\/p>\n<p style=\"text-align: left;\">\u5bb6\u8c31\u662f\u4eba\u4eec\u8ffd\u601d\u5148\u7956\u3001\u94ed\u8bb0\u8840\u7f18\u5173\u7cfb\u7684\u6700\u91cd\u8981\u7684\u5de5\u5177\u3002\u5bb6\u8c31\u4e2d\u8bb0\u5f55\u7684\u662f\u76f8\u540c\u59d3\u6c0f\u7684\u5bb6\u65cf\u6210\u5458\u3002\u4eba\u4eec\u7684\u59d3\u6c0f\u5927\u591a\u7ee7\u627f\u81ea\u7236\u4eb2\uff0c\u800cY \u67d3\u8272\u4f53\u662f\u4e25\u683c\u7684\u7236\u5b50\u76f8\u4f20\u7684\u57fa\u56e0\u7ec4\u7247\u6bb5\u3002\u6240\u4ee5\u59d3\u6c0f\u4e0eY \u67d3\u8272\u4f53\u7684\u9057\u4f20\u5e94\u8be5\u662f\u5e73\u884c\u7684\uff0c\u6709\u5171\u540c\u59d3\u6c0f\u7684\u7537\u6027\u53ef\u80fd\u6709\u76f8\u540c\u6216\u76f8\u8fd1\u7684Y \u67d3\u8272\u4f53\u7c7b\u578b\u3002\u7136\u800c\uff0c\u591a\u8d77\u6e90\u3001\u6539\u59d3\u3001\u975e\u4eb2\u751f\u3001\u4ece\u6bcd\u59d3\u7b49\u793e\u4f1a\u56e0\u7d20\u5f31\u5316\u4e86\u67d0\u4e9b\u59d3\u6c0f\u4e0eY \u67d3\u8272\u4f53\u7684\u5173\u8054\uff0c\u6b64\u65f6\u57fa\u56e0\u7814\u7a76\u53ef\u4e3a\u5398\u6e05\u7236\u7cfb\u8840\u7f18\u63d0\u4f9b\u7ebf\u7d22\u3002Y \u67d3\u8272\u4f53\u4e0a\u7a33\u5b9a\u7684SNP \u70b9\u7a81\u53d8\u53ef\u4ee5\u6c38\u8fdc\u5728\u7236\u7cfb\u540e\u4ee3\u4e2d\u6d41\u4f20\uff0c\u53ef\u4ee5\u6784\u5efa\u53ef\u9760\u7684\u7236\u7cfb\u57fa\u56e0\u8c31\u7cfb\uff1b\u800c\u5176\u4e0a\u7a81\u53d8\u8f83\u5feb\u7684STR \u5fae\u536b\u661f\u4f4d\u70b9\u53c8\u53ef\u4ee5\u7528\u4ee5\u4f30\u7b97\u65f6\u95f4\u3002\u56e0\u6b64\uff0cY \u67d3\u8272\u4f53\u53ef\u7528\u4ee5\u7814\u7a76\u5f88\u591a\u59d3\u6c0f\u5b97\u65cf\u7684\u5386\u53f2\uff0c\u751a\u81f3\u5343\u767e\u5e74\u524d\u7684\u5386\u53f2\u7591\u6848\u3002\u91cd\u5efa\u59d3\u6c0f\u3001\u5bb6\u8c31\u4e0eY \u67d3\u8272\u4f53\u7684\u5173\u7cfb\u5fc5\u5c06\u6210\u4e3a\u5386\u53f2\u4eba\u7c7b\u5b66\u7814\u7a76\u7684\u91cd\u8981\u5185\u5bb9\u3002<\/p>\n<p style=\"text-align: center;\"><strong>\u5b97\u65cf\u59d3\u6c0f\u4e0eY\u67d3\u8272\u4f53\u7684\u7236\u7cfb\u9057\u4f20<\/strong><\/p>\n<p style=\"text-align: left;\">\u7236\u7cfb\u9057\u4f20\u5173\u7cfb\uff0c\u662f\u5bb6\u8c31\u4e2d\u8bb0\u8f7d\u7684\u4e3b\u8981\u9057\u4f20\u5173\u7cfb\u3002\u867d\u7136\u59d3\u6c0f\u666e\u904d\u9075\u4ece\u7236\u7cfb\u9057\u4f20\uff0c\u4f46\u4e5f\u5e76\u4e0d\u5b8c\u5168\u3002\u5c31\u4e2d\u56fd\u793e\u4f1a\u60c5\u51b5\u800c\u8a00\uff0c\u6536\u517b\u3001\u7ee7\u517b\u3001\u5165\u8d58\uff0c\u751a\u81f3\u76f4\u63a5\u6539\u59d3\uff0c\u90fd\u4f1a\u5f71\u54cd\u59d3\u6c0f\u4e0e\u7236\u7cfb\u8840\u7edf\u7684\u5173\u8054\u7a0b\u5ea6\u3002\u5f88\u591a\u5f71\u54cd\u7236\u7cfb\u9057\u4f20\u5173\u7cfb\u7684\u60c5\u51b5\u5e76\u4e0d\u88ab\u5fe0\u5b9e\u8bb0\u5f55\u5728\u5bb6\u8c31\u4e2d\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u4e2d\u56fd\u5927\u591a\u6570\u59d3\u6c0f\u8d77\u6e90\u4e8e\u6625\u79cb\u65f6\u671f\u7684\u5404\u4e2a\u5c01\u56fd\uff0c\u5c01\u56fd\u5185\u7684\u767e\u59d3\u90fd\u4ee5\u56fd\u4e3a\u59d3\u7684\u65f6\u5019\uff0c\u8fd9\u4e9b\u540c\u56fd\u767e\u59d3\u7684\u8840\u7edf\u53ef\u80fd\u672c\u6765\u5c31\u4e0d\u4e00\u81f4\uff0c\u8fd9\u5c31\u9020\u6210\u4e86\u5f88\u591a\u6bd4\u8f83\u5927\u7684\u59d3\u6c0f\u5185\u90e8\u9057\u4f20\u7ed3\u6784\u7684\u4e0d\u4e00\u81f4\uff0c\u4ea6\u5373\u540c\u59d3\u4e0d\u4e00\u5b9a\u540c\u6e90\u3002<\/p>\n<p style=\"text-align: left;\">\u4e0e\u59d3\u6c0f\u4e0d\u540c\uff0c\u4eba\u7c7b\u7684Y\u67d3\u8272\u4f53\u76f4\u63a5\u4ee3\u8868\u7740\u7236\u7cfb\u9057\u4f20\uff0c\u6c38\u8fdc\u662f\u7236\u5b50\u76f8\u4f20\u7684\uff0c\u4e0d\u4f1a\u53d7\u5230\u4efb\u4f55\u793e\u4f1a\u6587\u5316\u548c\u81ea\u7136\u56e0\u7d20\u7684\u5f71\u54cd\u3002\u4eba\u4f53\u5185\u670923\u5bf9\u67d3\u8272\u4f53\uff0c\u5176\u4e2d22\u5bf9\u5e38\u67d3\u8272\u4f53\u4e2d\uff0c\u6bcf\u4e00\u5bf9\u67d3\u8272\u4f53\u90fd\u6709\u4e00\u6761\u6765\u81ea\u7236\u7cfb\uff0c\u4e00\u6761\u6765\u81ea\u6bcd\u7cfb\uff0c\u4e24\u6761\u67d3\u8272\u4f53\u5728\u4f20\u4ee3\u8fc7\u7a0b\u4e2d\u5bf9\u5e94\u7684\u90e8\u5206\u4f1a\u53d1\u751f\u4ea4\u6362\uff0c\u4ece\u800c\u9020\u6210\u6df7\u8840\u6548\u5e94\uff0c\u8fd9\u5c31\u662f\u9057\u4f20\u5b66\u4e0a\u8bf4\u7684\u91cd\u7ec4\u3002\u53e6\u4e00\u5bf9\u6027\u67d3\u8272\u4f53\u5305\u62ecX\u67d3\u8272\u4f53\u548cY\u67d3\u8272\u4f53\u3002\u5728\u5973\u6027\u4f53\u5185\uff0cX\u67d3\u8272\u4f53\u4e5f\u662f\u6210\u5bf9\u7684\uff0c\u5206\u522b\u6765\u81ea\u7236\u6bcd\u53cc\u65b9\uff0c\u6240\u4ee5\u4e5f\u4e0d\u80fd\u907f\u514d\u6df7\u8840\u7684\u5f71\u54cd\u3002\u800c\u5728\u7537\u6027\u4f53\u5185\uff0c\u5374\u53ea\u6709\u4e00\u6761\u6765\u81ea\u6bcd\u4eb2\u7684X\u67d3\u8272\u4f53\u548c\u4e00\u6761\u6765\u81ea\u7236\u4eb2\u7684Y\u67d3\u8272\u4f53\uff0c\u4e5f\u5c31\u662f\u8bf4\u7537\u6027\u7684Y\u67d3\u8272\u4f53\u53ea\u80fd\u6765\u6e90\u4e8e\u7236\u4eb2\uff0c\u6240\u4ee5\u4eba\u4f53\u6027\u67d3\u8272\u4f53\u7684\u9057\u4f20\u65b9\u5f0f\u51b3\u5b9a\u4e86Y\u67d3\u8272\u4f53\u9075\u4ece\u4e25\u683c\u7684\u7236\u7cfb\u9057\u4f20\u3002<\/p>\n<p style=\"text-align: left;\">Y\u67d3\u8272\u4f53\u4e0eX\u67d3\u8272\u4f53\u4e4b\u95f4\u662f\u5426\u4f1a\u53d1\u751f\u91cd\u7ec4\u5462\uff1f\u8981\u56de\u7b54\u8fd9\u4e2a\u95ee\u9898\uff0c\u5fc5\u987b\u5148\u4e86\u89e3Y\u67d3\u8272\u4f53\u7684\u7ed3\u6784\u3002\u4eba\u7c7bY\u67d3\u8272\u4f53DNA\u5927\u7ea6\u5305\u542b\u516d\u5343\u4e07\u4e2a\u78b1\u57fa\u5bf9\uff0c\u5176\u4e2d\u67d3\u8272\u4f53\u4e24\u7aef\u76845%\u4e3a\u62df\u5e38\u67d3\u8272\u4f53\u533a\u57df\uff0c\u5728\u4f20\u4ee3\u8fc7\u7a0b\u4e2d\u4e0eX\u67d3\u8272\u4f53\u76f8\u5e94\u533a\u6bb5\u4f1a\u53d1\u751f\u91cd\u7ec4\uff0c\u800c\u4e3b\u5e72\u90e8\u5206\u768495\uff05\u4e3a\u975e\u91cd\u7ec4\u533a\u57df\uff0c\u4e0d\u4e0e\u4efb\u4f55\u67d3\u8272\u4f53\u53d1\u751f\u91cd\u7ec4\u3002\u6240\u4ee5\uff0cY\u67d3\u8272\u4f53\u4e3b\u5e72\u90e8\u5206\u7684\u6b64\u7279\u6027\uff0c\u4fdd\u8bc1\u4e86\u5b50\u4ee3\u80fd\u5b8c\u6574\u5730\u7ee7\u627f\u7236\u4ee3\u7684Y\u67d3\u8272\u4f53\u4e3b\u5e72\u800c\u4e0d\u53d7\u6df7\u8840\u5f71\u54cd\uff0c\u4fdd\u8bc1\u4e86Y\u67d3\u8272\u4f53\u4e3b\u5e72\u7684\u4e25\u683c\u7236\u7cfb\u9057\u4f20\u3002\u8fd9\u662f\u4e00\u6761\u4e0d\u80fd\u7be1\u6539\u7684\u57fa\u56e0\u5bb6\u8c31\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-914 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu02.jpg\" alt=\"\" width=\"554\" height=\"401\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu02.jpg 554w, https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu02-300x217.jpg 300w, https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu02-500x362.jpg 500w\" sizes=\"auto, (max-width: 554px) 100vw, 554px\" \/><\/p>\n<p style=\"text-align: center;\">\u4eba\u7c7bY\u67d3\u8272\u4f53\u6a21\u5f0f\u4ee5\u53ca\u59d3\u6c0f\u548cY\u67d3\u8272\u4f53\u7684\u5171\u540c\u7236\u7cfb\u4f20\u9012<\/p>\n<p>\u6240\u4ee5\uff0c\u5f53\u4f5a\u5931\u7684\u6216\u8005\u4e0d\u5fe0\u5b9e\u8bb0\u8f7d\u7684\u59d3\u6c0f\u5bb6\u8c31\u5df2\u7ecf\u65e0\u6cd5\u4f5c\u4e3a\u8ffd\u5bfb\u7956\u5148\u7684\u53ef\u9760\u4f9d\u636e\u7684\u65f6\u5019\uff0c\u4ee5\u73b0\u4ee3\u7684\u5206\u5b50\u751f\u7269\u5b66\u6280\u672f\u4e3a\u57fa\u7840\uff0c\u7814\u7a76Y\u67d3\u8272\u4f53\u4e3b\u5e72\u7684\u7c7b\u578b\uff0c\u662f\u76f4\u63a5\u8ffd\u6eaf\u5b97\u65cf\u59d3\u6c0f\u6210\u5458\u4e4b\u95f4\u7684\u7236\u7cfb\u5173\u7cfb\u7684\u6700\u4f73\u65b9\u6cd5\uff0c\u662f\u9a8c\u8bc1\u7956\u5148\u4e0e\u540e\u4ee3\u7684\u7236\u7cfb\u5173\u8054\uff0c\u8865\u5168\u5bb6\u8c31\u7684\u552f\u4e00\u624b\u6bb5\u3002\u4f8b\u5982\uff0c\u5728\u66f9\u64cd\u7684\u540e\u4eba\u4e2d\u5206\u6790Y\u67d3\u8272\u4f53\u7279\u5f81\uff0c\u6211\u4eec\u5c31\u53ef\u4ee5\u4e86\u89e3\u66f9\u64cd\u672c\u4eba\u7684Y\u67d3\u8272\u4f53\u7279\u5f81\uff0c\u4e5f\u53ef\u4ee5\u4e86\u89e3\u73b0\u4ee3\u66f9\u6c0f\u540e\u4eba\u4e4b\u95f4\u7684\u4eb2\u7f18\u8fdc\u8fd1\u3002\u5b9e\u9645\u4e0a\uff0c\u5728\u4e00\u6bb5\u6709\u8f83\u53ef\u4fe1\u5386\u53f2\u8bb0\u5f55\u7684\u65f6\u671f\u5185\uff0c\u6574\u4e2a\u5bb6\u65cf\u7684\u59d3\u6c0f\u4e0e\u7236\u7cfb\u9057\u4f20\u7684\u5173\u8054\u662f\u53ef\u4ee5\u4fdd\u8bc1\u7684\uff0c\u6240\u4ee5\u5bb6\u65cf\u7684\u59d3\u6c0f\u5f80\u5f80\u4e0e\u56fa\u5b9a\u7684Y\u67d3\u8272\u4f53\u7c7b\u578b\u5171\u540c\u4f20\u9012\uff0c\u7d27\u5bc6\u5173\u8054\u3002<\/p>\n<p style=\"text-align: center;\"><strong>\u7a33\u5b9a\u4e2d\u53d8\u5316\u7740\u7684Y\u67d3\u8272\u4f53<\/strong><\/p>\n<p>\u5728\u4e00\u4ee3\u4e00\u4ee3\u7684\u7236\u5b50\u76f8\u627f\u7684\u4f20\u9012\u8fc7\u7a0b\u4e2d\uff0cY\u67d3\u8272\u4f53\u4e5f\u5728\u6162\u6162\u5730\u79ef\u7d2f\u7740\u53d8\u5316\u3002\u6b63\u662f\u56e0\u4e3a\u9057\u4f20\u7a81\u53d8\u7684\u79ef\u7d2f\uff0c\u4f7f\u5f97\u4eba\u7c7b\u7236\u7cfb\u9057\u4f20\u4f53\u7cfb\u4e2d\uff0c\u8ddd\u79bb\u8d8a\u8fdc\u7684\u4e2a\u4f53\u7684Y\u67d3\u8272\u4f53\u5dee\u5f02\u4e5f\u8d8a\u5927\u3002Y\u67d3\u8272\u4f53\u4e0a\u7684\u7a81\u53d8\u5f62\u6210\u7684\u4e2a\u4f53\u5dee\u5f02\u4e3b\u8981\u6709\u4e24\u5927\u7c7b\uff0c\u5355\u6838\u82f7\u9178\u591a\u6001(SNP)\u548c\u77ed\u4e32\u8054\u91cd\u590d(STR)\u3002DNA\u5206\u5b50\u7531\u56db\u79cd\u78b1\u57fa(A\u3001T\u3001C\u3001G)\u6309\u7167\u4e00\u5b9a\u7684\u987a\u5e8f\u8fde\u63a5\u800c\u6210\uff0cSNP\u662f\u4ec5\u4ec5\u4e00\u4e2a\u4f4d\u7f6e\u4e0a\u7684\u78b1\u57fa\u7c7b\u578b\u53d8\u5316\u3002Y\u67d3\u8272\u4f53\u4e0a\u7684\u540c\u4e00\u4e2aSNP\u5728\u4eba\u7fa4\u4e2d\u4e00\u822c\u53ea\u6709\u4e24\u79cd\u7c7b\u578b\u3002STR\u5219\u662f\u5728\u67d3\u8272\u4f53\u7684\u7279\u5b9a\u533a\u6bb5\uff0c\u7531\u51e0\u4e2a\u78b1\u57fa\u7ec4\u6210\u4e00\u4e2a\u5355\u4f4d\u91cd\u590d\u51fa\u73b0\uff0c\u4e0d\u540c\u7684Y\u67d3\u8272\u4f53\u4e0a\u7684\u540c\u4e00\u4e2aSTR\u4f4d\u7f6e\u5f80\u5f80\u6709\u4e0d\u540c\u7684\u91cd\u590d\u62f7\u8d1d\u6570\u3002SNP\u548cSTR\u7531\u4e8e\u7a81\u53d8\u6027\u8d28\u548c\u7a81\u53d8\u901f\u5ea6\u4e0d\u540c\uff0c\u5728\u5206\u6790\u4e2d\u6709\u7740\u4e0d\u540c\u7684\u7528\u9014\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-917 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu03.jpg\" alt=\"\" width=\"553\" height=\"503\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu03.jpg 553w, https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu03-300x273.jpg 300w\" sizes=\"auto, (max-width: 553px) 100vw, 553px\" \/><\/p>\n<p style=\"text-align: center;\">\u77ed\u4e32\u8054\u91cd\u590d(STR)\u548c\u5355\u6838\u82f7\u9178\u591a\u6001(SNP)\u7684\u4e24\u79cd\u7a81\u53d8\u7c7b\u578b\u533a\u522b<\/p>\n<p>\u8981\u786e\u7acb\u7236\u7cfb\u9057\u4f20\u4f53\u7cfb\uff0c\u6700\u91cd\u8981\u7684\u524d\u63d0\u662f\u7956\u5148\u7684\u7a81\u53d8\u53ef\u4ee5\u7a33\u5b9a\u7684\u4fdd\u7559\u5728\u540e\u4ee3\u7684Y\u67d3\u8272\u4f53\u4e0a\u3002SNP\u7a81\u53d8\u56e0\u4e3a\u7a81\u53d8\u901f\u7387\u6781\u4f4e\uff0c\u53ef\u4ee5\u505a\u5230\u5728\u540e\u4ee3\u4e2d\u6c38\u4e45\u5730\u4fdd\u7559\uff0c\u540e\u4ee3\u53ea\u80fd\u5728\u7956\u5148\u7684\u7a81\u53d8\u57fa\u7840\u4e0a\u79ef\u7d2f\u65b0\u7684\u7a81\u53d8\uff0c\u800c\u4e0d\u4f1a\u4e22\u5931\u7956\u5148\u7684\u7a81\u53d8\u7279\u5f81\u3002\u901a\u8fc7\u6bd4\u8f83\u4eba\u7c7b\u4e0e\u9ed1\u7329\u7329\u7684Y\u67d3\u8272\u4f53\u5dee\u5f02\uff0c\u4ee5\u53ca\u5927\u5bb6\u7cfb\u4e2d\u7684Y\u67d3\u8272\u4f53\u7684\u5dee\u5f02\u7a0b\u5ea6\uff0cY\u67d3\u8272\u4f53\u4e0a\u7684SNP\u7a81\u53d8\u7684\u901f\u7387\u88ab\u8ba1\u7b97\u4e86\u51fa\u6765\u3002\u6bcf\u51fa\u751f\u4e00\u4e2a\u7537\u5b50\uff0c\u4e00\u4e2a\u67d3\u8272\u4f53\u4f4d\u7f6e\u4e0a\u53d1\u751fSNP\u7a81\u53d8\u7684\u6982\u7387\u4e3a\u5927\u7ea6\u4e09\u5343\u4e07\u5206\u4e4b\u4e00\u3002\u5b9e\u9645\u4e0a\u7531\u4e8eY\u5e38\u67d3\u8272\u8d28\u533a\u7684\u4fdd\u5b88\u6027\uff0c\u4ee5\u53ca\u4eba\u7c7b\u5386\u53f2\u4e0a\u5927\u91cf\u7537\u5b50\u90fd\u6ca1\u6709\u7537\u6027\u540e\u4ee3\u4fdd\u7559\u81f3\u4eca\u7684\u4e8b\u5b9e\uff0c\u5b9e\u9645\u7684\u7fa4\u4f53\u4e2d\u7a81\u53d8\u7387\u5e94\u8be5\u4f4e\u51e0\u4e2a\u6570\u91cf\u7ea7\u3002\u800c\u6211\u4eec\u901a\u5e38\u7814\u7a76\u7684\u662fY\u67d3\u8272\u4f53\u975e\u91cd\u7ec4\u533a\u5927\u7ea6\u4e09\u5343\u4e07\u4e2a\u78b1\u57fa\u5bf9\u7684\u5e38\u67d3\u8272\u8d28\u533a\uff0c\u6309\u7167\u6bcf\u4e2a\u78b1\u57fa\u5bf9\u4e09\u5343\u4e07\u5206\u4e4b\u4e00\u7684\u7a81\u53d8\u7387\uff0c\u8fd9\u4e2a\u533a\u6bb5\u5185\u6bcf\u4e2a\u7537\u5b50\u5e73\u5747\u90fd\u4f1a\u6709\u4e00\u4e2a\u65b0\u7684\u7a81\u53d8\u3002\u8fd9\u4e2a\u65b0\u7684\u7a81\u53d8\u968f\u673a\u5730\u51fa\u73b0\u5728Y\u5e38\u67d3\u533a\u7684\u4efb\u610f\u4e00\u4e2a\u70b9\u4e0a\uff0c\u5982\u679c\u8fd9\u4e2a\u7a81\u53d8\u4e86\u7684\u70b9\u4e0a\u518d\u53d1\u751f\u4e00\u6b21\u7a81\u53d8\uff0c\u90a3\u4e48\u8fd9\u4e2a\u7a81\u53d8\u5c31\u5728\u540e\u4ee3\u4e2d\u4e22\u5931\u4e86\uff0c\u6211\u4eec\u5c31\u65e0\u6cd5\u901a\u8fc7\u540e\u4ee3\u786e\u5b9a\u7956\u5148\u7684Y\u67d3\u8272\u4f53\u7a81\u53d8\u8c31\u3002\u4f46\u662f\uff0c\u540c\u4e00\u4e2a\u70b9\u4e0a\u5148\u540e\u53d1\u751f\u4e24\u6b21\u7a81\u53d8\u7684\u6982\u7387\uff0c\u6309\u7167\u6982\u7387\u8ba1\u7b97\u65b9\u6cd5\u5c31\u662f\u4e09\u5343\u4e07\u5206\u4e4b\u4e00\u7684\u5e73\u65b9\uff0c\u4e5f\u5c31\u662f\u4e5d\u767e\u4e07\u4ebf\u5206\u4e4b\u4e00\uff0c\u76f8\u5bf9\u4e8e\u4eba\u7c7b\u81ea\u53e4\u4ee5\u6765\u7684\u4eba\u53e3\uff0c\u8fd9\u4e2a\u6982\u7387\u5c31\u8fd1\u4f3c\u4e8e\u96f6\u3002\u6240\u4ee5\u6211\u4eec\u53ef\u4ee5\u8bf4\uff0c\u7edd\u5927\u591a\u6570\u60c5\u51b5\u4e0b\uff0c\u7956\u5148\u7684Y\u67d3\u8272\u4f53\u4e0a\u51fa\u73b0\u7684SNP\u7a81\u53d8\u7279\u5f81\u5728\u540e\u4ee3\u4e2d\u80fd\u591f\u627e\u5230\uff0c\u800c\u540e\u4ee3\u53ea\u80fd\u5728\u7956\u5148Y\u67d3\u8272\u4f53\u7a81\u53d8\u8c31\u7684\u57fa\u7840\u4e0a\u589e\u52a0\u65b0\u7684\u7a81\u53d8\u3002<\/p>\n<p>\u7531\u591a\u4e2aSNP\u7a81\u53d8\u6784\u6210\u7684\u4e00\u79cd\u7a81\u53d8\u7cfb\u5217\u7ec4\u5408\u88ab\u79f0\u4e3a\u4e00\u79cd\u5355\u500d\u578b\u3002\u4f8b\u5982\u4e0b\u56fe\u4e2d\u5c31\u67095\u4e2aSNP\u7a81\u53d8\uff0c\u9646\u7eed\u6784\u62105\u79cd\u5355\u500d\u578b\u3002\u5176\u4e2d1\u578b\u662f\u5176\u4ed6\u5355\u500d\u578b\u7684\u7956\u5148\u578b\uff0c\u5176\u4ed6\u5355\u500d\u578b\u90fd\u662f\u540e\u4ee3\u578b\u3002\u7956\u5148\u578b\u4e0e\u6240\u6709\u540e\u4ee3\u578b\u5408\u79f0\u4e3a\u4e00\u4e2a\u5355\u500d\u7fa4\u3002\u4e00\u4e2a\u5bb6\u65cf\u7684\u6240\u6709Y\u67d3\u8272\u4f53\u7406\u8bba\u4e0a\u90fd\u5c5e\u4e8e\u4e00\u4e2a\u5355\u500d\u7fa4\uff0c\u56e0\u4e3a\u5176\u4e2d\u6240\u6709\u7684\u7537\u6027\u90fd\u5e94\u8be5\u6765\u81ea\u540c\u4e00\u4e2a\u7956\u5148\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-919 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu04.jpg\" alt=\"\" width=\"550\" height=\"405\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu04.jpg 550w, https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu04-300x221.jpg 300w, https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu04-280x207.jpg 280w\" sizes=\"auto, (max-width: 550px) 100vw, 550px\" \/><\/p>\n<p style=\"text-align: center;\">Y\u67d3\u8272\u4f53\u7a81\u53d8\u8c31\u53ef\u4ee5\u6784\u6210\u5355\u500d\u578b\u7684\u539f\u7406<\/p>\n<p>\u5f53\u7136\uff0c\u5355\u500d\u7fa4\u7684\u6982\u5ff5\u53ef\u5927\u53ef\u5c0f\u3002\u5927\u800c\u8a00\u4e4b\uff0c\u5168\u4e16\u754c\u7684Y\u67d3\u8272\u4f53\u90fd\u5c5e\u4e8e\u4e00\u79cd\u5355\u500d\u7fa4\uff0c\u90fd\u6765\u81ea20\u591a\u4e07\u5e74\u524d\u7684\u4e00\u4e2a\u4e1c\u975e\u665a\u671f\u667a\u4eba\u7537\u5b50\u3002\u8fdb\u800c\uff0c\u5168\u4e16\u754c\u53c8\u53ef\u4ee5\u5206\u4e3a20\u79cd\u4e3b\u5e72\u5355\u500d\u7fa4\uff0c\u7f16\u53f7\u4eceA\u5230T\u3002\u6700\u53e4\u8001\u7684A\u548cB\u5355\u500d\u7fa4\u90fd\u6ca1\u6709\u8d70\u51fa\u975e\u6d32\uff0cC\u548cD\u5355\u500d\u7fa4\u6700\u65e9\u6765\u5230\u4e86\u6fb3\u6d32\u548c\u4e9a\u6d32\uff0cE\u5355\u500d\u7fa4\u6765\u5230\u4e86\u4e9a\u6d32\u53c8\u56de\u5230\u975e\u6d32\uff0cF\u5355\u500d\u7fa4\u884d\u751f\u51faGHIJ\u7b49\u5355\u500d\u7fa4\u5728\u897f\u65b9\u5f62\u6210\u6b27\u7f57\u5df4\u4eba\u79cd\uff0c\u884d\u751f\u51faK\u5355\u500d\u7fa4\u5e76\u5f62\u6210NOPQ\u7b49\u5355\u500d\u7fa4\u5728\u4e1c\u65b9\u5f62\u6210\u8499\u53e4\u4eba\u79cd\uff0c\u5176\u4e2dO\u5355\u500d\u7fa4\u6210\u4e3a\u4e86\u4e2d\u56fd\u4eba\u7684\u4e3b\u6d41\uff0c\u800cQ\u5355\u500d\u7fa4\u6210\u4e3a\u7f8e\u6d32\u5370\u7b2c\u5b89\u4eba\u7684\u4e3b\u6d41\u3002\u6240\u4ee5\uff0cY\u67d3\u8272\u4f53\u7684\u8c31\u7cfb\u6784\u5efa\u51fa\u4e86\u5168\u4eba\u7c7b\u7684\u4e00\u90e8\u5927\u5bb6\u8c31\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-921 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu05.jpg\" alt=\"\" width=\"1949\" height=\"1180\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu05.jpg 1949w, https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu05-300x182.jpg 300w, https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu05-768x465.jpg 768w, https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu05-1024x620.jpg 1024w\" sizes=\"auto, (max-width: 1949px) 100vw, 1949px\" \/><\/p>\n<p style=\"text-align: center;\"><strong>Y\u67d3\u8272\u4f53\u4e0a\u7684\u65f6\u949f<\/strong><\/p>\n<p>\u5229\u7528Y\u67d3\u8272\u4f53\u4e0a\u7a33\u5b9a\u9057\u4f20\u7684SNP\uff0c\u6211\u4eec\u53ef\u4ee5\u6784\u5efa\u51fa\u4e2a\u4f53\u6216\u5bb6\u65cf\u4e4b\u95f4\u660e\u786e\u7684\u9057\u4f20\u6e0a\u6e90\u3002\u800c\u4e14\uff0c\u65e2\u7136SNP\u6709\u7a33\u5b9a\u7684\u7a81\u53d8\u901f\u7387\uff0c\u5f53\u6211\u4eec\u7edf\u8ba1\u51fa\u4e0d\u540c\u4eba\u7684Y\u67d3\u8272\u4f53\u4e4b\u95f4\u7684\u7a81\u53d8\u5dee\u5f02\u6570\uff0c\u5c06\u5dee\u5f02\u6570\u9664\u4ee5\u901f\u7387\uff0c\u7ecf\u8fc7\u6362\u7b97\u5c31\u53ef\u4ee5\u4f30\u7b97\u4e24\u6761Y\u67d3\u8272\u4f53\u4e4b\u95f4\u7684\u5206\u5316\u65f6\u95f4\uff0c\u8fd9\u5c31\u662f\u8ba1\u91cf\u8fdb\u5316\u65f6\u95f4\u7684\u201c\u5206\u5b50\u949f\u201d\u3002\u4f46\u662f\uff0c\u7531\u4e8eSNP\u7684\u7a81\u53d8\u901f\u7387\u5b9e\u5728\u592a\u4f4e\uff0c\u4e2a\u4f53\u4e4b\u95f4\u7684\u7a81\u53d8\u5dee\u5f02\u6563\u5e03\u5728Y\u67d3\u8272\u4f53\u7684\u5404\u5904\uff0c\u53ea\u80fd\u4f7f\u7528Y\u67d3\u8272\u4f53\u5168\u6d4b\u5e8f\u6765\u5bfb\u627e\uff0c\u800c\u76ee\u524d\u5168\u6d4b\u5e8f\u7684\u6210\u672c\u592a\u9ad8\uff0c\u5c1a\u4e0d\u80fd\u666e\u904d\u5e94\u7528\u3002\u8fd9\u4e00\u7f3a\u70b9\u88abY\u67d3\u8272\u4f53\u4e0a\u7684\u53e6\u4e00\u9057\u4f20\u6807\u8bb0STR\u5f25\u8865\u4e86\u3002<\/p>\n<p>\u4e00\u4e9bSTR\u4f4d\u70b9\u5206\u5e03\u5728Y\u67d3\u8272\u4f53\u4e0a\u7684\u56fa\u5b9a\u4f4d\u7f6e\uff0c\u6bcf\u4e00\u4e2aSTR\u4f4d\u70b9\u5185\u90e8\u7684\u91cd\u590d\u5355\u4f4d\u5728\u4f20\u4ee3\u8fc7\u7a0b\u4e2d\u6539\u53d8\u7740\u62f7\u8d1d\u6570\uff0c\u8fd9\u79cd\u6539\u53d8\u4e5f\u662f\u6709\u7740\u56fa\u5b9a\u7684\u901f\u7387\u7684\u3002\u800cSTR\u7a81\u53d8\u901f\u7387\u8981\u6bd4SNP\u5927\u5f97\u591a\uff0c\u5728\u5bb6\u7cfb\u4e2d\u6bcf\u51fa\u751f\u4e00\u4e2a\u7537\u5b50\u6bcf\u4e2aSTR\u4f4d\u70b9\u7a81\u53d8\u6982\u7387\u5927\u7ea6\u662f\u4e09\u767e\u5206\u4e4b\u4e00\u3002\u4e00\u822c\u7684Y\u67d3\u8272\u4f53\u5206\u6790\u4e2d\uff0c\u6211\u4eec\u8c03\u67e515\u4e2aSTR\u4f4d\u70b9\uff0c\u5176\u603b\u4f53\u7a81\u53d8\u7387\u5927\u7ea6\u662f\u4e8c\u5341\u5206\u4e4b\u4e00\u3002\u800cY\u67d3\u8272\u4f53\u4e0a\u5927\u7ea6\u6709150\u4e2a4\uff5e6\u4e2a\u6838\u82f7\u9178\u91cd\u590d\u7684STR\uff0c\u5982\u679c\u5206\u6790\u5168\u90e8\u7684STR\u4f4d\u70b9\uff0c\u90a3\u4e48\u603b\u7a81\u53d8\u7387\u5927\u7ea6\u662f\u4e8c\u5206\u4e4b\u4e00\u3002\u8fd9\u4e00\u9ad8\u7a81\u53d8\u7387\u5c31\u975e\u5e38\u6709\u5229\u4e8e\u4f30\u7b97\u4e0d\u540cY\u67d3\u8272\u4f53\u4e4b\u95f4\u7684\u5206\u5316\u65f6\u95f4\uff0c\u56e0\u6b64STR\u4f4d\u70b9\u6210\u4e3a\u4e86Y\u67d3\u8272\u4f53\u4e0a\u7684\u201c\u65f6\u949f\u201d\u3002<\/p>\n<p>STR\u7684\u7a81\u53d8\u662f\u53cc\u5411\u6027\u7684\uff0c\u62f7\u8d1d\u6570\u53ef\u4ee5\u589e\u52a0\u6216\u51cf\u5c11\u3002\u6709\u540c\u4e00\u7956\u5148\u7684\u4e0d\u540c\u4e2a\u4f53\u7684\u540c\u4e00STR\u4f4d\u70b9\uff0c\u53ef\u80fd\u6709\u4e0d\u540c\u7a81\u53d8\u65b9\u5411\u548c\u91cd\u590d\u6570\u3002\u540cSNP\u4e00\u6837\uff0c\u6570\u4e2a\u4e0d\u540c\u4f4d\u7f6e\u4e0a\u7684STR\u4e5f\u53ef\u4ee5\u6784\u6210\u5355\u500d\u578b\u3002\u5728\u7fa4\u4f53\u4e2d\u5206\u6790STR\u5355\u500d\u578b\u7684\u591a\u6837\u6027\u7a0b\u5ea6\u53ef\u4ee5\u8ba1\u7b97\u7fa4\u4f53\u7684\u5171\u7956\u65f6\u95f4\u3002\u5047\u8bbe\u4e00\u4e2aSTR\u6bcf\u6b21\u7a81\u53d8\u90fd\u53ea\u589e\u52a0\u6216\u8005\u51cf\u5c11\u4e00\u4e2a\u91cd\u590d\u5355\u4f4d\uff0c\u4e5f\u5c31\u662f\u4e00\u6b65(single-step)\u7a81\u53d8\u6a21\u578b\uff0c\u4e14\u7fa4\u4f53\u6709\u7740\u6052\u5b9a\u7684\u6709\u6548\u7fa4\u4f53\u5927\u5c0f\uff0c\u5c31\u53ef\u7531\u516c\u5f0ft=-Ne\u00d7ln(1-V\/Ne\u00d7\u03bc)\u63a8\u7b97\u51fa\u67d0\u7279\u5b9aY-SNP\u53d1\u751f\u7684\u5927\u81f4\u65f6\u95f4\u3002\u516c\u5f0f\u4e2d\uff0cNe\u662f\u6709\u6548\u7fa4\u4f53\u5927\u5c0f\uff0c\u03bc\u662f\u7a81\u53d8\u7387\uff0cln\u662f\u81ea\u7136\u5bf9\u6570\uff0cV\u662f\u89c2\u5bdf\u5230\u7684\u7fa4\u4f53\u4e2d\u7684\u67d0\u4e00STR\u6570\u503c\u7684\u65b9\u5dee\uff0c\u8ba1\u7b97\u5f97\u5230\u7684t\u662f\u7ecf\u5386\u7684\u4e16\u4ee3\u6570\uff0c\u518d\u4e58\u4ee5\u6bcf\u4e00\u4e16\u4ee3\u7684\u5e74\u6570\u5373\u53ef\u5f97\u5230\u65f6\u95f4\u3002<\/p>\n<p>\u4ee5Y\u67d3\u8272\u4f53\u4e0aSTR\u7684\u603b\u7a81\u53d8\u7387\u4e8c\u5206\u4e4b\u4e00\u6765\u4f30\u7b97\uff0c\u51e0\u4e4e\u6bcf\u4e2a\u4eba\u53ef\u4ee5\u6784\u6210\u72ec\u7279\u7684\u5355\u500d\u578b\u3002\u7136\u800c\uff0c\u7531\u4e8e\u7a81\u53d8\u662f\u4e00\u6b65\u4e00\u6b65\u53d1\u751f\u7684\uff0c\u7236\u7cfb\u4eb2\u7f18\u5173\u7cfb\u8d8a\u8fd1\u7684\u4e2a\u4f53\u4e4b\u95f4\u7684STR\u5355\u500d\u578b\u8d8a\u76f8\u4f3c\uff0c\u4e00\u4e2a\u7eaf\u7cb9\u7531\u7236\u7cfb\u4f20\u9012\u7684\u59d3\u6c0f\u5e94\u6709\u76f8\u8fd1\u7684STR\u5355\u500d\u578b\u3002\u4f46\u662f\uff0c\u7531\u4e8eSTR\u7684\u7a81\u53d8\u901f\u7387\u7684\u4e0d\u7a33\u5b9a\u6027\uff0c\u52a0\u4e0a\u56de\u590d\u7a81\u53d8\u7684\u5f71\u54cd\uff0cSTR\u8ba1\u7b97\u65f6\u95f4\u7684\u8bef\u5dee\u8fd8\u662f\u6781\u5927\u3002\u6240\u4ee5\uff0c\u51c6\u786e\u5730\u5206\u6790Y\u67d3\u8272\u4f53\u5355\u500d\u7fa4\u7684\u5206\u5316\u65f6\u95f4\uff0c\u8fd8\u662f\u8981\u7528\u5168Y\u67d3\u8272\u4f53SNP\u7684\u7a81\u53d8\u8c31\uff0c\u5728\u8fd9\u65b9\u9762\uff0c\u590d\u65e6\u5927\u5b66\u7684\u4eba\u7c7b\u5b66\u5b9e\u9a8c\u5ba4\u7684\u7814\u7a76\u8d70\u5728\u4e86\u4e16\u754c\u6700\u524d\u6cbf\u3002\u7406\u8bba\u4e0a\uff0c\u6709\u4e86\u8db3\u591f\u6570\u91cf\u7684Y\u67d3\u8272\u4f53SNP\u548cSTR\u540e\uff0c\u901a\u8fc7\u8c03\u67e5\u4e00\u4e2a\u59d3\u6c0f\u5b97\u65cf\u5185\u7684\u7537\u6027\u7684\u5355\u500d\u578b\uff0c\u5c31\u80fd\u591f\u5f88\u6e05\u695a\u7684\u6784\u5efa\u5176\u5bb6\u65cfY\u67d3\u8272\u4f53\u7684\u8c31\u7cfb\u6811\uff0c\u4e43\u81f3\u7f16\u5199\u4e00\u90e8\u6e05\u6670\u7684\u57fa\u56e0\u5bb6\u8c31\u3002<\/p>\n<p style=\"text-align: center;\"><strong>Y\u67d3\u8272\u4f53\u7814\u7a76\u59d3\u6c0f\u5bb6\u8c31\u7684\u5b9e\u8df5<\/strong><\/p>\n<p>\u591a\u9879\u7814\u7a76\u8bc1\u5b9e\u5404\u56fd\u7684\u59d3\u6c0f\u4f20\u627f\u662f\u76f8\u5bf9\u7a33\u5b9a\u7684\u3002\u5229\u7528Y\u67d3\u8272\u4f53\u6765\u68c0\u6d4b\u5386\u53f2\u4e0a\u7684\u5bb6\u65cf\u5173\u7cfb\u7591\u6848\uff0c\u6709\u591a\u9879\u6210\u529f\u7684\u6848\u4f8b\uff0c\u8f83\u6709\u610f\u601d\u7684\u662f\u7f8e\u56fd\u7b2c\u4e09\u4efb\u603b\u7edf\u6258\u9a6c\u65af\u2022\u6770\u6590\u900a\u56e0\u88ab\u6000\u7591\u4e0e\u5973\u4ec6\u6709\u8fc7\u5b69\u5b50\u800c\u906d\u8d77\u8bc9\uff0c\u901a\u8fc7\u6bd4\u5bf9\u6770\u6590\u900a\u7684\u53d4\u53d4\u3001\u5973\u4ec6\u7684\u4e24\u4e2a\u513f\u5b50\u7684\u7537\u6027\u540e\u4ee3Y\u67d3\u8272\u4f53\u591a\u6001\u4f4d\u70b9\uff0c\u6700\u7ec8\u7ed3\u8bba\u6770\u6590\u900a\u662f\u5973\u4ec6\u7684\u6700\u5c0f\u513f\u5b50\u7684\u751f\u7236\u3002Y\u67d3\u8272\u4f53\u4e0d\u4f46\u80fd\u591f\u89e3\u51b3\u6570\u767e\u5e74\u7684\u7591\u6848\uff0c\u8fd8\u80fd\u8ffd\u6eaf\u5230\u6570\u5343\u5e74\u524d\u7684\u5386\u53f2\u5e76\u8bc1\u5b9e\u4e86\u5723\u7ecf\u4e2d\u7684\u4f20\u8bf4\u3002\u5723\u7ecf\u4e2d\u8bb0\u8f7d\uff0c\u72b9\u592a\u4eba\u4e2d\u7684\u796d\u53f8\u662f\u7531\u72b9\u592a\u6559\u7684\u7b2c\u4e00\u796d\u53f8\u957fAaron\u5f00\u59cb\u6309\u8840\u7f18\u4ee3\u4ee3\u76f8\u4f20\uff0c\u800c\u8eab\u4e3a\u5fb7\u7cfb\u72b9\u592a\u4eba\u796d\u53f8\u7684Skorecki\u53d1\u73b0\u4ed6\u4e0e\u4e00\u4e2a\u897f\u73ed\u7259\u7cfb\u72b9\u592a\u4eba\u796d\u53f8\u7684\u4f53\u8d28\u7279\u5f81\u5dee\u522b\u5f88\u5927\uff0c\u4e3a\u6b64\u4ed6\u548c\u7814\u7a76Y\u67d3\u8272\u4f53\u7684\u4e13\u5bb6Hammer\u6559\u6388\u5408\u4f5c\uff0c\u4ee5Y\u67d3\u8272\u4f53\u4e0a\u591a\u6001\u4f4d\u70b9YAP\u548cDYS19\u6765\u5206\u6790\u72b9\u592a\u6559\u796d\u53f8\u7684\u5355\u500d\u578b\uff0c\u7ed3\u679c\u663e\u793a\uff0c\u5fb7\u7cfb\u548c\u897f\u73ed\u7259\u7cfb\u7684\u72b9\u592a\u796d\u53f8\u4e0e\u975e\u796d\u53f8\u7684\u72b9\u592a\u4eba\u76f8\u6bd4\u6709\u8f83\u8fd1\u7684\u4eb2\u7f18\u5173\u7cfb\u3002\u4e5f\u5c31\u662f\u8bf4\uff0c\u796d\u53f8\u4eec\u53ef\u8de8\u8d8a3 300\u5e74\u8ffd\u6eaf\u5230\u4e00\u4e2a\u5171\u540c\u7684\u7236\u7cfb\u7956\u5148\u3002Y\u67d3\u8272\u4f53\u7684\u5206\u6790\u4e0e\u5723\u7ecf\u6545\u4e8b\u7684\u5b8c\u7f8e\u5951\u5408\u7740\u5b9e\u8ba9\u4eba\u5403\u60ca\u3002<\/p>\n<p>\u5bf9\u4e8e\u4e2d\u56fd\u7684\u59d3\u6c0f\u4e0eY\u67d3\u8272\u4f53\u7684\u76f8\u5173\u6027\uff0c\u4e5f\u6709\u8bb8\u591a\u7814\u7a76\u89c1\u8bf8\u62a5\u9053\u3002\u591a\u9879\u7814\u7a76\u5bf9\u540c\u4e00\u5730\u533a\u5185\u5c45\u4f4f\u7684\u674e\u59d3\u3001\u738b\u59d3\u548c\u5f20\u59d3\u7b49\u65e0\u5173\u7537\u6027\u4e2a\u4f53Y\u67d3\u8272\u4f53\u9057\u4f20\u591a\u6001\u6027\u5206\u6790\u8868\u660e\uff0c\u6b64\u4e09\u59d3\u6c0f\u65e0\u5173\u7537\u6027\u4e2a\u4f53Y\u67d3\u8272\u4f53\u7684\u9057\u4f20\u591a\u6001\u6027\u4e30\u5bcc\uff0c\u4e0e\u4e0d\u540c\u59d3\u7684\u6c49\u65cf\u65e0\u5173\u7537\u6027\u7fa4\u4f53\u9057\u4f20\u591a\u6837\u6027\u6bd4\u8f83\u5dee\u5f02\u4e0d\u663e\u8457\u3002\u8fd9\u8bf4\u660e\uff0c\u6c49\u65cf\u7684\u5927\u59d3\u5185\u90e8\u57fa\u672c\u6ca1\u6709\u540c\u6e90\u6027\uff0c\u76f8\u5173Y\u67d3\u8272\u4f53\u7814\u7a76\u53ea\u80fd\u5728\u660e\u786e\u7684\u59d3\u6c0f\u5b97\u65cf\u4e2d\u5f00\u5c55\u3002\u5b97\u65cf\u7684\u8c31\u7cfb\u6574\u7406\u53ea\u80fd\u901a\u8fc7Y\u67d3\u8272\u4f53\u8fdb\u884c\uff0c\u800c\u4e0d\u80fd\u4ec5\u51ed\u540c\u59d3\u6216\u540c\u7956\u5c45\u5730\u63a8\u65ad\u3002<\/p>\n<p>\u6c49\u65cf\u5927\u59d3\u6c0f\u5185\u90e8\u7684\u4e0d\u4e00\u81f4\uff0c\u6709\u5f88\u591a\u53ef\u80fd\u7684\u539f\u56e0\u3002\u5728\u7406\u60f3\u7684\u60c5\u5f62\u4e0b\uff0c\u6bcf\u79cd\u59d3\u6c0f\u90fd\u6709\u4e00\u4e2a\u552f\u4e00\u6765\u6e90\uff0c\u5373\u8be5\u59d3\u6c0f\u7684\u5960\u57fa\u8005\u53ea\u662f\u4e00\u4eba\u6216\u662f\u6709\u76f8\u540cY\u67d3\u8272\u4f53\u5355\u500d\u578b\u7684\u591a\u4eba\uff0c\u5728\u59d3\u6c0f\u4f20\u627f\u8fc7\u7a0b\u4e2d\u6ca1\u6709\u53d1\u751f\u8fc7\u5e72\u6270(\u6539\u59d3\u3001\u975e\u4eb2\u751f\u7b49)\uff0c\u6b64\u65f6\u4e00\u79cd\u59d3\u6c0f\u53ef\u4ee5\u88ab\u4e00\u79cdSNP\u548cSTR\u7684\u5355\u500d\u578b\u6765\u9274\u5b9a\u3002\u4f46\u662f\u4e2d\u56fd\u7684\u5927\u591a\u6570\u59d3\u6c0f\u8d77\u6e90\u5e76\u4e0d\u5355\u4e00\u3002\u5468\u671d\u7684\u59d3\u6c0f\u5927\u591a\u662f\u4ee5\u5c01\u56fd\u4e3a\u6c0f\uff0c\u540e\u6539\u4e3a\u59d3\u3002\u6bd4\u5982\u66f9\u56fd\u7684\u738b\u5ba4\u540e\u4ee3\u59d3\u66f9\uff0c\u5176\u4ec6\u5f79\u540e\u4eba\u4e5f\u53ef\u4ee5\u59d3\u66f9\uff0c\u751a\u81f3\u6574\u4e2a\u5c01\u56fd\u5185\u6240\u6709\u767e\u59d3\u540e\u4ee3\u90fd\u53ef\u4ee5\u59d3\u66f9\u3002\u800c\u66f9\u56fd\u5185\u7684\u767e\u59d3\u6765\u6e90\u672c\u6765\u5c31\u662f\u591a\u6837\u7684\uff0c\u6709\u7740\u5404\u79cd\u5404\u6837\u7684Y\u67d3\u8272\u4f53\uff0c\u6240\u4ee5\u4e2d\u56fd\u7684\u59d3\u6c0f\u603b\u4f53\u4e0a\u5185\u90e8\u7236\u7cfb\u8840\u7f18\u4e0d\u4e00\u81f4\u3002<\/p>\n<p>\u53e6\u5916\uff0c\u72b9\u5982Y\u67d3\u8272\u4f53STR\u5355\u500d\u578b\u968f\u65f6\u95f4\u800c\u6f14\u5316\u51fa\u8d8a\u6765\u8d8a\u591a\u7684\u7c7b\u578b\u4e00\u6837\uff0c\u59d3\u6c0f\u5728\u4f20\u627f\u8fc7\u7a0b\u4e2d\u7ecf\u5386\u7684\u65f6\u95f4\u8d8a\u957f\uff0c\u5176\u53d7\u5230\u7684\u793e\u4f1a\u5e72\u6270\u8d8a\u591a\uff0c\u663e\u793a\u51fa\u7684\u5dee\u5f02\u4e5f\u8d8a\u5927\u3002\u5728\u4e2d\u56fd\uff0c\u59d3\u6c0f\u6709\u8fd15 000\u5e74\u7684\u5386\u53f2\uff0c\u6765\u6e90\u590d\u6742\u4e14\u5b58\u5728\u907f\u7978\u6539\u59d3\u3001\u907f\u8bb3\u6539\u59d3\u3001\u8fc7\u7ee7\u6539\u59d3\u3001\u7687\u5e1d\u8d50\u59d3\u4e0e\u8d2c\u59d3\u3001\u5c11\u6570\u6c11\u65cf\u7528\u6c49\u59d3\u7b49\u7b49\u95ee\u9898\u3002\u4e3e\u4e2a\u7b80\u5355\u7684\u4f8b\u5b50\uff0c\u4e2d\u56fd\u7684100\u4e2a\u5927\u59d3\u4e2d\u670953\u4e2a\u636e\u79f0\u6539\u81ea\u4e8e\u59ec\u59d3\u3002\u5982\u6b64\uff0c\u7814\u7a76\u4e2d\u56fd\u7684\u59d3\u6c0f\u96be\u5ea6\u6781\u5927\uff0c\u4f46\u662f\u4e2d\u56fd\u53c8\u6709\u7f16\u4fee\u5bb6\u8c31\u7684\u4f20\u7edf\uff0cY\u67d3\u8272\u4f53\u7684\u57fa\u56e0\u5bb6\u8c31\u7814\u7a76\u5c31\u5bf9\u5398\u6e05\u8fd9\u7eb7\u7e41\u590d\u6742\u7684\u8840\u7f18\u5173\u7cfb\u6709\u5f88\u5927\u5e2e\u52a9\u3002<\/p>\n<p>\u5bb6\u8c31\u662f\u4e00\u79cd\u4ee5\u8868\u8c31\u5f62\u5f0f\u8bb0\u8f7d\u67d0\u4e00\u540c\u5b97\u5171\u7956\u4ee5\u8840\u7f18\u5173\u7cfb\u4e3a\u4e3b\u4f53\u7684\u5bb6\u65cf\u4e16\u7cfb\u7e41\u884d\u517c\u53ca\u5176\u4ed6\u65b9\u9762\u60c5\u51b5\u7684\u7279\u6b8a\u56fe\u4e66\u4f53\u88c1\u3002\u4e5f\u5c31\u662f\u8bf4\uff0c\u5165\u8c31\u8005\u5fc5\u987b\u662f\u540c\u5b97\u5171\u7956\uff0c\u5373\u4f7f\u540c\u59d3\uff0c\u82e5\u4e0d\u540c\u7956\uff0c\u4e5f\u4e0d\u80fd\u4fee\u5165\u4e00\u90e8\u5bb6\u8c31\u4e4b\u4e2d\u3002\u5728\u4e2d\u56fd\u7684\u5e7f\u5927\u519c\u6751\uff0c\u4eba\u4eec\u4e00\u76f4\u6709\u7740\u540c\u59d3\u805a\u5c45\u7684\u4e60\u4fd7\uff0c\u52a0\u4e0a\u5a5a\u59fb\u534a\u5f84\u8f83\u5c0f\uff0c\u7531\u5bb6\u8c31\u786e\u5b9a\u7684\u67d0\u4e00\u5730\u57df\u5185\u540c\u59d3\u4eba\u7fa4\uff0c\u53ef\u4ee5\u8ba4\u4e3a\u662f\u6709\u76f8\u540c\u6216\u76f8\u8fd1Y\u67d3\u8272\u4f53\u7684\u7236\u7cfb\u9694\u79bb\u7fa4\u4f53\uff0c\u8fd9\u4e5f\u5c31\u4e3a\u5206\u5b50\u4eba\u7c7b\u5b66\u5206\u6790Y\u67d3\u8272\u4f53DNA\u591a\u6837\u6027\u63d0\u4f9b\u4e86\u6781\u597d\u7684\u7814\u7a76\u6a21\u578b\u3002<\/p>\n<p>\u7136\u800c\uff0c\u67d0\u4e9b\u5bb6\u8c31\u91cc\u6709\u5047\u6258\u3001\u501f\u6284\u7684\u5185\u5bb9\uff0c\u56e0\u6b64\u5bf9\u4e8e\u5bb6\u8c31\u8d44\u6599\u7684\u4f7f\u7528\u5fc5\u987b\u5ba1\u614e\u3002\u4f46\u662f\uff0c\u5728Y\u67d3\u8272\u4f53\u68c0\u9a8c\u8fd9\u79cd\u65e0\u53ef\u8fa9\u9a73\u7684\u79d1\u5b66\u8bc1\u636e\u9762\u524d\uff0c\u4efb\u4f55\u5bb6\u8c31\u90fd\u53ef\u4ee5\u5f97\u5230\u68c0\u9a8c\u548c\u4fee\u6b63\u3002\u59d3\u6c0f\u3001\u5bb6\u8c31\u548cY\u67d3\u8272\u4f53\u7684\u5173\u8054\u7814\u7a76\u5fc5\u7136\u6210\u4e3a\u793e\u4f1a\u5927\u4f17\u7f16\u5236\u5bb6\u8c31\u7684\u65b0\u5229\u5668\uff0c\u6210\u4e3a\u7814\u7a76\u4e2d\u56fd\u4eba\u8d77\u6e90\u4e0e\u6f14\u53d8\u7684\u91cd\u8981\u65b9\u5f0f\uff0c\u5f00\u521b\u5386\u53f2\u4eba\u7c7b\u5b66\u7814\u7a76\u7684\u65b0\u7bc7\u7ae0\u3002<\/p>\n<p>\u4f5c\u8005\uff1a\u674e \u8f89\uff08\u590d\u65e6\u5927\u5b66\u73b0\u4ee3\u4eba\u7c7b\u5b66\u6559\u80b2\u90e8\u91cd\u70b9\u5b9e\u9a8c\u5ba4\uff09<\/p>\n<p style=\"text-align: center;\"><strong>\u600e\u6837\u5bf9\u4e00\u4e2a\u4eba\u7684\u57fa\u56e0\u7ec4\u8fdb\u884c\u6d4b\u5e8f\uff1f<\/strong><\/p>\n<p>\u8fd9\u4e2aTED\u7684\u79d1\u666e\u89c6\u9891\u5f62\u8c61\u5730\u544a\u8bc9\u5927\u5bb6\u79d1\u5b66\u5bb6\u4eec\u662f\u5982\u4f55\u5bf9\u57fa\u56e0\u7ec4\u8fdb\u884c\u6d4b\u5e8f\u7684\u3002<\/p>\n<figure class=\"wp-block-video aligncenter\"><video src=\"https:\/\/www.liu.world\/wp-content\/uploads\/HowToSequenceTheHumanGenome.mp4\" poster=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/02\/Poster_HowToSequenceTheHumanGenome.jpg\" controls=\"controls\" width=\"100%\" height=\"100%\"><br \/>\n<\/video><\/figure>\n<p style=\"text-align: center;\">\u300a\u5982\u4f55\u5bf9\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8fdb\u884c\u6d4b\u5e8f\u300b\uff08\u9a6c\u514b.J.\u57fa\u5c14\uff09<\/p>\n<p>\u4f60\u5927\u6982\u5df2\u7ecf\u542c\u8bf4\u8fc7\u4ec0\u4e48\u662f\u4eba\u7c7b\u57fa\u56e0\u7ec4\u2014\u2014\u5b83\u662f\u5de8\u91cf\u7684\u57fa\u56e0\u603b\u548c\uff0c\u5e76\u4e14\u5728\u4f60\u8eab\u4f53\u4e2d\u6bcf\u4e00\u4e2a\u7ec6\u80de\u91cc\u90fd\u6709\u4e00\u4efd\u3002\u4f60\u5f88\u53ef\u80fd\u4e5f\u77e5\u9053\u6211\u4eec\u5df2\u7ecf\u5bf9\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8fdb\u884c\u4e86\u6d4b\u5e8f\uff0c\u4f46\u8fd9\u5230\u5e95\u662f\u4ec0\u4e48\u610f\u601d\uff1f\u600e\u6837\u5bf9\u4e00\u4e2a\u4eba\u7684\u57fa\u56e0\u7ec4\u8fdb\u884c\u6d4b\u5e8f\uff1f<\/p>\n<p>\u5148\u8bb2\u70b9\u80cc\u666f\u77e5\u8bc6\u3002<\/p>\n<p><strong>\u4ec0\u4e48\u662f\u57fa\u56e0\u7ec4\uff1f<\/strong><\/p>\n<p>\u7b80\u5355\u6765\u8bf4\uff0c\u57fa\u56e0\u7ec4\uff0c\u5c31\u662f\u5168\u90e8\u7684\u57fa\u56e0\u518d\u52a0\u4e0a\u70b9\u522b\u7684\u7269\u8d28\u5171\u540c\u7ec4\u6210\u7684\u4e00\u4e2a\u6709\u673a\u4f53\u3002\u57fa\u56e0\u7531DNA\u7ec4\u6210\uff0c\u800cDNA\u662f\u6210\u5bf9\u7684\u957f\u94fe\uff0c\u7531A(\u817a\u560c\u5464)\uff0cT(\u80f8\u817a\u5627\u5576)\uff0cC(\u80de\u5627\u5576)\u548cG(\u9e1f\u560c\u5464)\u7ec4\u6210\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1224 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome01.jpg\" alt=\"\" width=\"640\" height=\"341\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome01.jpg 640w, https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome01-300x160.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/p>\n<p>\u4f60\u7684\u57fa\u56e0\u7ec4\u5c31\u50cf\u662f\u4e00\u7ec4\u4ee3\u7801\uff0c\u4f60\u7684\u7ec6\u80de\u9700\u8981\u901a\u8fc7\u5b83\u6765\u77e5\u9053\u81ea\u5df1\u5728\u4ec0\u4e48\u65f6\u5019\u8be5\u505a\u4e9b\u4ec0\u4e48\u3002<strong>\u7ec6\u80de\u4ea4\u7ec7\u5728\u4e00\u8d77\u6210\u4e3a\u4e86\u7ec4\u7ec7\uff0c\u4e0d\u540c\u7684\u7ec4\u7ec7\u76f8\u4e92\u534f\u8c03\u6784\u6210\u4e86\u5668\u5b98\uff0c\u800c\u5668\u5b98\u534f\u540c\u5de5\u4f5c\u5f62\u6210\u4e86\u751f\u547d\u4f53\uff0c\u4e5f\u5c31\u662f\u4f60\uff01\u56e0\u6b64\u4f60\u4e4b\u6240\u4ee5\u662f\u4f60\uff0c\u5f88\u5927\u7a0b\u5ea6\u4e0a\u6e90\u81ea\u4e8e\u4f60\u7684\u57fa\u56e0\u7ec4\u3002<\/strong><\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1225 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome02.jpg\" alt=\"\" width=\"395\" height=\"647\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome02.jpg 395w, https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome02-183x300.jpg 183w\" sizes=\"auto, (max-width: 395px) 100vw, 395px\" \/><\/p>\n<p>\u7b2c\u4e00\u4e2a\u4eba\u7c7b\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u7ed3\u679c\u7684\u771f\u6b63\u5b8c\u6210\u65f6\u95f4\u662f2003\u5e74\u3002\u5f53\u65f6\u975e\u5e38\u8270\u96be\uff0c<strong>\u5b83\u82b1\u4e8615\u5e74\u624d\u5b8c\u6210\uff08\u89c6\u9891\u4e2d\u662f20\u5e74\uff0c\u8fd9\u5176\u5b9e\u662f\u6709\u4e89\u8bae\u7684\uff09<\/strong>\uff0c\u671f\u95f4\u6709\u6765\u81ea\u5168\u4e16\u754c\u51e0\u5341\u4e2a\u56fd\u5bb6\u548c\u5730\u533a\u51e0\u767e\u4f4d\u79d1\u5b66\u5bb6\u7684\u8f9b\u82e6\u4ed8\u51fa\uff0c\u800c\u4e14\u8d39\u7528\u8d85\u8fc730\u4ebf\u7f8e\u5143\u3002<strong>\u4f46\u73b0\u5728\u5374\u53ea\u9700\u8981\u6570\u5929\u65f6\u95f4\uff0c\u8d39\u7528\u4e0d\u8fc76000\u4eba\u6c11\u5e01\u3002<\/strong>\u6211\u4eec\u5df2\u7ecf\u53ef\u4ee5\u5c55\u671b\u5728\u4e0d\u4e45\u7684\u5c06\u6765\uff0c\u53ea\u8981\u51e0\u5206\u949f\u65f6\u95f4\uff0c\u5c31\u80fd\u641e\u6e05\u7ec4\u6210\u4f60\u8fd9\u4e2a\u4eba\u7684\u57fa\u56e0\u7ec4\u7684\u5b57\u6bcd\u6392\u5217\uff0c\u8d39\u7528\u751a\u81f3\u8fd8\u4e0d\u53ca\u4e00\u4efd\u8f83\u597d\u7684\u751f\u65e5\u793c\u7269\u8d35\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1226 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome03.jpg\" alt=\"\" width=\"640\" height=\"434\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome03.jpg 640w, https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome03-300x203.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/p>\n<p>\u4f46\u8fd9\u8981\u600e\u4e48\u505a\u5462\uff1f\u8ba9\u6211\u6765\u89e3\u91ca\u4e00\u4e0b\uff0c\u5f04\u6e05\u4f60\u57fa\u56e0\u7ec4\u4e2d\u8fd9\u51e0\u5341\u4ebf\u4e2a\u5b57\u6bcd\u7684\u6392\u5217\u987a\u5e8f\uff0c\u662f\u57fa\u56e0\u6d4b\u5e8f\u7684\u57fa\u672c\u76ee\u6807\u3002<strong>\u57fa\u56e0\u7ec4\u65e2\u5f88\u5927\u5f88\u5927\uff0c\u53c8\u5f88\u5c0f\u5f88\u5c0f\u3002<\/strong>DNA\u4e2d\u7684\u6bcf\u4e2a\u5b57\u6bcd\uff0c\u5c31\u662fA\u3001T\u3001C\u3001G\uff0c\u5bbd\u5ea6\u53ea\u67098-10\u4e2a\u539f\u5b50\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1227 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome04.jpg\" alt=\"\" width=\"640\" height=\"561\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome04.jpg 640w, https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome04-300x263.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/p>\n<p>\u800c\u5b83\u4eec\u5728\u7ec6\u80de\u4e2d\u5168\u90e8\u7f20\u7ed5\u5728\u4e00\u8d77\u6210\u4e3a\u4e00\u56e2\uff0c\u5c31\u50cf\u4e00\u56e2\u6bdb\u7ebf\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1228 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome05.jpg\" alt=\"\" width=\"640\" height=\"335\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome05.jpg 640w, https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome05-300x157.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/p>\n<p>\u6240\u4ee5\u8981\u4ece\u8fd9\u4e48\u5c0f\u7684\u5730\u65b9\u83b7\u53d6\u6240\u6709\u7684\u8fd9\u4e9bDNA\u4fe1\u606f\uff0c\u79d1\u5b66\u5bb6\u9996\u5148\u8981\u628aDNA\u7684\u957f\u94fe\u6253\u65ad\u4e3a\u8bb8\u591a\u77ed\u94fe\u3002\u7136\u540e\u628a\u6bcf\u4e00\u6bb5\u5206\u79bb\u51fa\u6765\u5355\u72ec\u6d4b\u5e8f\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1229 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome06.jpg\" alt=\"\" width=\"640\" height=\"304\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome06.jpg 640w, https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome06-300x143.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/p>\n<p>\u90a3\u4e48\uff0c\u5230\u5e95\u600e\u4e48\u6d4b\uff1f\u4f60\u8fd9\u6837\u60f3\u4e00\u4e0b\u6216\u8bb8\u4f1a\u66f4\u5bb9\u6613\u7406\u89e3\uff1a\u5f53DNA\u4e0a\u5f7c\u6b64\u4e4b\u95f4\u7684\u5e8f\u5217\u521a\u597d\u4e92\u8865\u7684\u8bdd\uff0c\u8fd9\u4e00\u6761DNA\u5c31\u4f1a\u548c\u5176\u5b83DNA\u4ea4\u5408\uff1a<strong>A\u914dT\uff0cT\u914dA\uff0cG\u914dC\uff0cC\u914dG\u3002<\/strong><\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1230 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome07.jpg\" alt=\"\" width=\"640\" height=\"462\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome07.jpg 640w, https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome07-300x217.jpg 300w, https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome07-500x362.jpg 500w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/p>\n<p>\u90a3\u4e48\uff0c\u5982\u679c\u4e24\u7247DNA\u7684\u5e8f\u5217\u521a\u597d\u80fd\u591f\u4e92\u8865\uff0c\u5b83\u4eec\u5c31\u4f1a\u7ed3\u5408\u5728\u4e00\u8d77\u3002<strong>\u4f46\u7531\u4e8e\u57fa\u56e0\u7247\u6bb5\u975e\u5e38\u5c0f\uff0c\u6211\u4eec\u9700\u8981\u67d0\u4e9b\u529e\u6cd5\u6765\u653e\u5927\u8fd9\u4e9b\u4fe1\u53f7\uff0c\u8fd9\u6837\u624d\u80fd\u68c0\u6d4b\u5230\u6bcf\u4e2a\u5b57\u6bcd\u662f\u4ec0\u4e48\u3002\u79d1\u5b66\u5bb6\u6700\u5e38\u7528\u7684\u65b9\u6cd5\uff0c\u662f\u7528\u9176\u6765\u628a\u539f\u6765\u7684\u57fa\u56e0\u7247\u6bb5\u591a\u5408\u6210\u51fa\u51e0\u5343\u4efd\uff08\u4ee5\u6b64\u5c06\u539f\u6765\u7684\u4fe1\u53f7\u653e\u5927\u51e0\u5343\u51e0\u4e07\u500d\uff09\u3002<\/strong>\u8fd9\u6837\u6211\u4eec\u5c31\u80fd\u591f\u91c7\u7528\u4e00\u4e9b\u6280\u672f\u624b\u6bb5\u8fdb\u884c\u68c0\u6d4b\u4e86\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1231 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome08.jpg\" alt=\"\" width=\"640\" height=\"348\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome08.jpg 640w, https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome08-300x163.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/p>\n<p>\u7ecf\u8fc7\u590d\u5236\u4e4b\u540e\uff0c\u63a5\u4e0b\u6765\u6211\u4eec\u8981\u505a\u7684\u5c31\u662f\u628a\u5168\u90e8\u7684\u8fd9\u4e9b\u5e8f\u5217\u4fe1\u606f\u90fd\u8bfb\u53d6\u51fa\u6765\u3002\u4e3a\u4e86\u505a\u5230\u8fd9\u4e00\u70b9\uff0c\u6211\u4eec\u9700\u8981\u518d\u5236\u4f5c\u4e00\u6279\u7279\u522b\u7684\u5b57\u6bcd\uff0c\u6bcf\u79cd\u90fd\u6709\u7279\u6b8a\u7684\u989c\u8272\u3002<\/p>\n<p>\u628a\u8fd9\u4e9b\u5e26\u989c\u8272\u6807\u8bb0\u7684\u5b57\u6bcd\u548c\u9176\u6df7\u5408\u5728\u4e00\u8d77\u540e\uff0c\u518d\u52a0\u5165\u5230\u6211\u4eec\u8bd5\u56fe\u9605\u8bfb\u7684\u8fd9\u4e2a\u57fa\u56e0\u7ec4\u91cc\u3002\u8fd9\u6837\uff0c\u5728\u5316\u5b66\u53cd\u5e94\u7684\u4f5c\u7528\u4e0b\uff0c\u57fa\u56e0\u7ec4\u4e0a\u7684\u6bcf\u4e2a\u4f4d\u70b9\uff0c\u90fd\u6709\u8fd9\u6837\u4e00\u4e2a\u7279\u6b8a\u5b57\u6bcd\u548c\u5bf9\u5e94\u7684\u5b57\u6bcd\u7ed3\u5408\uff0c\u4ece\u800c\u5f62\u6210\u4e00\u6bb5\u53cc\u94feDNA\uff0c\u800c\u4e14\u5728\u65b0\u5408\u6210\u7684DNA\u4e0a\u6bcf\u4e2a\u5b57\u6bcd\u4e0a\u90fd\u5e26\u6709\u989c\u8272\u6807\u8bb0\u3002<\/p>\n<p>\u7136\u540e\uff0c\u79d1\u5b66\u5bb6\u4eec\u5bf9\u6bcf\u4e00\u5c0f\u6bb5\u57fa\u56e0\u7ec4\u8fdb\u884c\u7167\u76f8\uff0c\u4e4b\u540e\uff0c\u6211\u4eec\u5c31\u53ef\u4ee5\u770b\u5230\u4e00\u4e9b\u5217\u989c\u8272\u70b9\u7684\u6392\u5217\u987a\u5e8f\uff0c\u63a5\u7740\uff0c\u6211\u4eec\u5c31\u53ef\u4ee5\u901a\u8fc7\u8fd9\u4e9b\u8272\u70b9\u8bfb\u51fa\u5e8f\u5217\u4e86\u3002\u6700\u540e\uff0c\u8fd9\u6837\u51e0\u767e\u4e07\uff08\u751a\u81f3\u51e0\u4ebf\uff09\u6761\u7684DNA\u7247\u6bb5\u4f1a\u7531\u8ba1\u7b97\u673a\u7a0b\u5e8f\u62fc\u63a5\u5728\u4e00\u8d77\uff0c\u6211\u4eec\u5c31\u80fd\u5f97\u5230\u8fd9\u6574\u4e2a\u57fa\u56e0\u7ec4\u7684\u5b8c\u6574\u5e8f\u5217\u3002<\/p>\n<p>\u867d\u7136\u8fd9\u5e76\u975e\u662f\u83b7\u53d6DNA\u5b57\u6bcd\u987a\u5e8f\u7684\u552f\u4e00\u65b9\u6cd5\uff0c\u4f46\u5374\u662f\u76ee\u524d\u6700\u5e38\u7528\u7684\u65b9\u6cd5\u3002<\/p>\n<p>\u5f53\u7136\uff0c\u4ec5\u4ec5\u53ea\u662f\u8bfb\u53d6\u57fa\u56e0\u7ec4\u4e2d\u7684\u5b57\u6bcd\u8fd8\u8fdc\u8fdc\u4e0d\u591f\u3002\u8fd9\u5c31\u597d\u6bd4\u4f60\u5728\u7ffb\u4e00\u672c\u4e66\uff0c\u4f60\u867d\u7136\u80fd\u8bfb\u51fa\u4e66\u91cc\u7684\u6bcf\u4e00\u4e2a\u5b57\u6bcd\uff0c\u4f46\u5374\u4e0d\u7406\u89e3\u4e66\u91cc\u8bf4\u4e86\u4ec0\u4e48\uff0c\u8fd9\u662f\u56e0\u4e3a\u4e66\u4e2d\u6240\u7528\u7684\u8bed\u8a00\u4f60\u5e76\u4e0d\u61c2\u3002<\/p>\n<p>\u6240\u4ee5\uff0c\u6d4b\u5e8f\u5b8c\u6210\u4e4b\u540e\uff0c<strong>\u4e0b\u4e00\u6b65\u91cd\u8981\u7684\u5de5\u4f5c\u5c31\u662f\u89e3\u7801\u51fa\u8fd9\u4e9b\u5e8f\u5217\u5230\u5e95\u662f\u4ec0\u4e48\u610f\u601d\u3002<\/strong>\u641e\u660e\u767d\u4e3a\u4ec0\u4e48\u4f60\u7684\u57fa\u56e0\u7ec4\u4f1a\u548c\u6211\u7684\u4e0d\u4e00\u6837\u3002\u9610\u91ca\u8fd9\u4e9b\u57fa\u56e0\u7ec4\u4e2d\u5404\u4e2a\u57fa\u56e0\u5143\u4ef6\u7684\u529f\u80fd\uff0c\u662f\u5f53\u4e0b\u79d1\u5b66\u5bb6\u4eec\u6b63\u5728\u8fdb\u884c\u7684\u5de5\u4f5c\uff0c\u867d\u7136\u5e76\u4e0d\u662f\u6bcf\u4e00\u5904\u4e0d\u540c\u4e4b\u5904\u90fd\u610f\u4e49\u91cd\u5927\uff0c\u4f46<strong>\u8fd9\u4e9b\u4e0d\u540c\u4e4b\u5904\u7ec4\u5408\uff08\u53e0\u52a0\uff09\u5728\u4e00\u8d77\uff0c\u5c31\u51b3\u5b9a\u4e86\u4eba\u4e0e\u4eba\u4e4b\u95f4\u7684\u4e0d\u540c\u3002<\/strong><\/p>\n<p><strong>\u5b83\u51b3\u5b9a\u4e86\u6211\u4eec\u7684\u5916\u8c8c\u770b\u8d77\u6765\u600e\u4e48\u6837\uff0c\u6211\u4eec\u559c\u6b22\u4ec0\u4e48\uff0c\u6211\u4eec\u5982\u4f55\u53cd\u5e94\uff0c\u751a\u81f3\u5305\u62ec\u6211\u4eec\u60a3\u4e0a\u67d0\u79cd\u75be\u75c5\u7684\u53ef\u80fd\u6027\uff0c\u4ee5\u53ca\u5bf9\u5404\u7c7b\u836f\u7269\u7684\u4e0d\u540c\u53cd\u5e94\u3002<\/strong><\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1232 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome09.jpg\" alt=\"\" width=\"640\" height=\"242\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome09.jpg 640w, https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome09-300x113.jpg 300w\" sizes=\"auto, (max-width: 640px) 100vw, 640px\" \/><\/p>\n<p>\u6240\u4ee5\uff0c\u66f4\u597d\u5730\u8ba4\u8bc6\u6211\u4eec\u5404\u81ea\u57fa\u56e0\u7ec4\u4e0a\u7684\u5dee\u522b\u4e4b\u5904\u610f\u4e49\u91cd\u5927\u3002\u540c\u65f6\uff0c\u5728\u8ba4\u8bc6\u5230\u8fd9\u4e9b\u5dee\u522b\u4e4b\u540e\uff0c\u4e5f\u5fc5\u5c06\u4f1a\u6539\u53d8\u6211\u4eec\u7684\u8bb8\u591a\u4f20\u7edf\u89c2\u5ff5\uff1a\u4e0d\u4ec5\u5305\u62ec\u533b\u751f\u5e94\u5f53\u5982\u4f55\u6cbb\u7597\u75c5\u4eba\uff0c\u4e5f\u5305\u62ec\u6211\u4eec\u5f7c\u6b64\u4e4b\u95f4\u8be5\u5982\u4f55\u66f4\u597d\u76f8\u5f85\u3002<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1233 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome10.jpg\" alt=\"\" width=\"543\" height=\"397\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome10.jpg 543w, https:\/\/www.liu.world\/wp-content\/uploads\/2019\/01\/HowToSequenceTheHumanGenome10-300x219.jpg 300w\" sizes=\"auto, (max-width: 543px) 100vw, 543px\" \/><\/p>\n<p>\u4f5c\u8005\uff1a\u9ec4\u6811\u5609 \u00a0\u00a0 \u9057\u4f20\u5b66\u535a\u58eb | \u516c\u4f17\u53f7: \u78b1\u57fa\u77ff\u5de5<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-933 size-full\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu06.jpg\" alt=\"\" width=\"500\" height=\"313\" srcset=\"https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu06.jpg 500w, https:\/\/www.liu.world\/wp-content\/uploads\/2018\/12\/jiyincexu06-300x188.jpg 300w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><\/p>\n<p style=\"text-align: center;\"><span style=\"color: #ff0000;\"><strong>\u4ee5\u4e0b\u5185\u5bb9\u9700\u8f93\u5165\u5bc6\u7801\u65b9\u53ef\u6d4f\u89c8<\/strong><\/span><\/p>\n<p style=\"text-align: center;\"><span style=\"color: #000000;\">\u5bc6\u7801\u63d0\u793a\uff1a\u300a\u59cb\u7956\u51a0\u695a\u5e9c\u541b\u8bb3\u5357\u4ef2\u66a8\u914d\u4f0d\u5b7a\u4eba\u8d5e\u300b\u7bc7\u9996\u516b\u4e2a\u5b57\u7684\u6c49\u8bed\u62fc\u97f3\uff0825\u4e2a\u5b57\u6bcd\uff09<\/span><\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-1379\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/2019\/05\/arrow_down.gif\" alt=\"\" width=\"200\" height=\"200\" \/><\/p>\n<p style=\"text-align: center;\"><strong><span style=\"color: #0000ff;\"><a style=\"color: #0000ff;\" href=\"https:\/\/www.liu.world\/?page_id=900\" target=\"_blank\" rel=\"noopener noreferrer\">\u57fa\u56e0\u68c0\u6d4b\u62a5\u544a<\/a><\/span><\/strong><\/p>\n<p style=\"text-align: center;\"><span style=\"color: #ff0000;\"><strong>\u65cf\u5185\u6d4f\u89c8 \u8bf7\u52ff\u5916\u4f20<\/strong><\/span><\/p>\n<p><embed hidden=\"true\" src=\"https:\/\/www.liu.world\/wp-content\/uploads\/StarWars.mp3\" type=\"audio\/mp3\" width=\"100%\" height=\"50\"><\/embed><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u57fa\u56e0\u6d4b\u5e8f\u6307\u5206\u6790\u7279\u5b9aDNA\u7247\u6bb5\u7684\u78b1\u57fa\u5e8f\u5217\uff0c\u5373\u817a\u560c\u5464\u3001\u80f8\u817a\u5627\u5576\u3001\u80de\u5627\u5576\u4e0e\u9e1f\u560c\u5464\u7684\u6392\u5217\u65b9\u5f0f\u3002 \u57fa\u56e0\u5bb6\u8c31 \u5bb6\u8c31\u662f\u4eba\u4eec\u8ffd [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-897","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.liu.world\/index.php?rest_route=\/wp\/v2\/pages\/897","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.liu.world\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.liu.world\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.liu.world\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.liu.world\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=897"}],"version-history":[{"count":70,"href":"https:\/\/www.liu.world\/index.php?rest_route=\/wp\/v2\/pages\/897\/revisions"}],"predecessor-version":[{"id":5584,"href":"https:\/\/www.liu.world\/index.php?rest_route=\/wp\/v2\/pages\/897\/revisions\/5584"}],"wp:attachment":[{"href":"https:\/\/www.liu.world\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=897"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}